Physiological principle for health and social care Essay

Physiological principle for health and social care - Essay Example ysis, deamination, fatty acid oxidations which enters the Tricarboxylic acid cycle or TCA cycle where it combines with oxaloacetic acid to form citrate and this is recycled back to oxaloacetate which continues the cycle again. There can be other intermediates of the TCA cycle which is derived from the breakdown products of carbohydrate , fats and proteins and thus it is not necessarily be acetyl CoA. In the TCA cycle, dehydrogenation takes place in the various molecules and carbon dioxide is liberated(which we finally breathe out). The removed hydrogen is taken up by NAD or FAD to form NADH and FADH2 . These molecules transfer the hydrogen atoms and the respected electrons through the electron transport chain which comprises of enzymatic complexes, that helps to transfer the electrons to the oxygen molecule ( which is inhaled and thus utilized un this fashion) with the formation of water. The hydrogen ions are pumped out of the inner mitochondrial matrix to the external space. This causes the hydrogen ion concentration to be more in external matrix than in the inner matrix. The hydrogen ions are pulled into the inner matrix due to passive diffusion through the half channels in the ATP synthase molecule that has a rotor-stator function. This means when the outside hydrogen atoms are pulled inside the ATP synthase causes a conformational change that puts the free ADP and Pi to its catalytic domain and thus ATP synthesis takes place.(Ganong, 2005)(Das,2009) 2. Whenever metabolism occurs in the body, there can be a change in the pH of the body which can hamper the action of various enzymes needed for completing other metabolic reactions therefore it is necessary to maintain an optimum pH or the acid base balance of the body to maintain homeostasis (keeping the internal environment of the body constant). This can be achieved by the compensatory mechanism which corrects alkalosis or acidosis under the changed conditions. The lungs help to correct acidosis by